The RICE method should be your first reaction. RICE stands for Rest, Ice, Compression and Elevation.
To learn a bit more on this method http://myfitnessdepot.com/sports-injuries/injury-first-aid-the-rice-method/
Another strategy could be to modify your running style. Recently, I have begun using a technique called ChiRunning ( http://www.chirunning.com ). In essence, ChiRunning aims to lessen the forces that most runners experience by introducing a slight forward lean and a biomechanically efficient flow to their running style. It advocates running with relaxed lower legs and using a mid-foot strike to avoid the braking and impact of heel strike. Since adopting the ChiRunning approach, I have found running even more enjoyable, not to mention less strenuous.